Rabies (or Hydrophobia) untreated is a usually fatal virus disease, almost always resulting from the bite of an infected dog.

The symptoms are malaise, headache and fever, violent movements, and hydrophobia - literally a fear of water - caused by paralysis of the swallowing muscles. These symptoms usually appear within a week, but occasionally are delayed for several months. Newspaper reports from the 1800s would also describe how affected patients would make barking noises and try to bite anyone close by.